the large trunk artery that carries blood from the left ventricle of the heart to branch arteries ; PULSE. 5 letter answer(s) to it comes from the heart. Our system collect crossword clues from most populer crossword, cryptic puzzle, quick/small crossword that found in Daily Mail, Daily Telegraph, Daily Express, Daily Mirror, Herald-Sun, The Courier-Mail and others popular newspaper. This crossword clue was last seen on February 11 2020 in the Free Themed Crossword Puzzles Puzzle. They come from the heart -- Find potential answers to this crossword clue at crosswordnexus.com Find answers for the crossword clue: It comes from the heart. Clue: It comes straight from the heart. This page shows answers to the clue Spirit, followed by ten definitions like “(19 related articles)”, “Air set in motion by breathing” and “SPace InfraRed Imaging Telescope”.Synonyms for Spirit are for example character, core and essence.More synonyms can be found below the puzzle answers. 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