lycopene benefits for men

The recommended intake is at least 10mg of lycopene per day—from food. According to MayoClinic.com, most clinical studies have focused on the amount of lycopene-containing foods that participants ate rather than on the specific quantities of lycopene they consumed. In this placebo-controlled trial, circulating lycopene concentration increased only after consumption of red tomato paste and purified lycopene. In a “Harvard University” study (1995) conducted with 47,894 men, researchers found that eating 10 or more servings a week of tomato products was linked with a reduced risk of prostate cancer by as much a 34%. To prevent or treat prostate cancer, two milligrams of lycopene has been taken by mouth twice daily, and four milligrams of lycopene has been taken by mouth twice daily for one year. Based on the above, FDA concludes that there is no credible evidence supporting a relationship between tomato or tomato-based food consumption and colorectal cancer. Pain Relief Lycopene is readily absorbed by the organism and is naturally present in human plasma and tissues in more concentrations than the other carotenoids. Protects the Heart: Lycopene rich foods prevent the oxidation of LDL (bad cholesterol) from clogging the arteries. Results from several in vitro and animal studies have indicated that lycopene may have chemopreventive effects for cancers of the prostate, skin, breast, lung, and liver; however, human trials have been inconsistent in their findings. Lycopene shows antioxidant and anticancer properties. Both petitioners requested that FDA evaluate the relationship between tomato and/or lycopene consumption and prostate cancer risk. White pre-cancerous patches in the mouth (oral leukoplakia). Early research shows that taking lycopene by along with antibiotics does not help treat H. pylori infection compared to taking antibiotics alone. Early research shows that taking lycopene by mouth, alone or together with other ingredients, might protect against sunburn. However, there does not appear to be a link between lycopene levels and stroke risk. Other studies have not found this link. Two LycoRed® softules (each containing 2,000 micrograms of lycopene) have been taken by mouth daily for six months. A Cochrane Review in 2011 concluded there is insufficient evidence to either support, or refute, the use of lycopene for the prevention of prostate cancer. Early research shows that taking a specific lycopene supplement by mouth twice daily improves white pre-cancerous patches in the mouth. Some evidence suggests that people with low lycopene levels are almost twice as likely to develop age-related eye disease compared to people with high levels. A dose of 250 milligrams of Lyc-O-Mato® has been taken by mouth for eight weeks 45). Lycopene is an antioxidant that is present in red- and pink-colored fruits and vegetables. However, measures of lycopene intake have been based on eating tomatoes, not on the use of lycopene supplements. Men with the greatest amounts of lycopene in their blood had a 55% lower chance of having any kind of stroke. Though it can be found as a … When the subjects consumed 8-16mg of the supplement for 12 weeks, the group suffered less severe skin reactions. Preliminary research in men with precancerous changes in their prostate shows that taking 4 mg of lycopene  twice daily might delay or prevent progression to prostate cancer. Sunburn. FDA concludes that it is highly uncertain that tomato sauce reduces the risk of ovarian cancer.”, The qualified health claim for pancreatic cancer was “One study suggests that consuming tomatoes does not reduce the risk of pancreatic cancer, but one weaker, more limited study suggests that consuming tomatoes may reduce this risk. Based on these studies, FDA concludes that it is unlikely that tomatoes reduce the risk of gastric cancer.”, The qualified health claim for ovarian cancer was “One study suggests that consumption of tomato sauce two times per week may reduce the risk of ovarian cancer; while this same study shows that consumption of tomatoes or tomato juice had no effect on ovarian cancer risk. The evidence for a relationship between tomato intake and reduced risk of breast cancer is based on two case control studies. Diabetes. A study conducted at the All “India Institute of Medical Sciences” found that lycopene, can boost sperm concentrations in infertile men. Lung cancer. An Italian study showed that people who ate at least one tomato-based product per day had a 50 percent lower chance of contracting digestive tract cancer than those who did not eat tomatoes. This pigment is a effective antioxidant that can help protect against degenerative diseases. There are numerous studies on the uses of lycopene in treating cancer and cardiovascular disease, as well as on its antioxidant and anti-inflammatory activity. Studies have found that Lycopene can protect your DNA, your prostate health, your skin and your bones. Age-related eye disease (age-related maculopathy). Serum lycopene decreases the risk of stroke in men : A population-based follow-up study. And at a recent conference, researchers presented findings on lycopene's potential protection against male infertility, osteoporosis, skin cancer, Varicose vein removal , eye disease, prostate, breast and endometrial cancers. Similarly, there is no robust evidence from randomised controlled trials to identify the impact of lycopene consumption upon the incidence of prostate cancer, prostate symptoms, PSA levels or adverse events 13). It is a great addition to any men's health regimen. The important carotenoids in the human body include; beta-carotene, alpha-carotene, lutein, cryptoxanthin, zeaxanthin and lycopene. But, there are also other lycopene benefits. The cell-protecting benefits are thought to fight off potentially harmful bodies that could turn into cancerous cells. Research suggests that there is no link between lycopene consumption in the diet or lycopene blood levels and the risk for bladder cancer. http://www.hmdb.ca/metabolites/HMDB03000, Arab L, Steck S: Lycopene and cardiovascular disease. Processed tomato products have high amounts of lycopene than raw tomatoes. 2004Q-0201). However, other studies have found no link between lycopene intake or lycopene blood levels and the risk of developing cataracts. Now, in a report just published in the journal Neurology, a team of Finnish researchers has linked lycopene levels in the blood to stroke protection 26). Women with higher levels of lycopene in their blood seem to recover from cancer-associated HPV infection faster than women with lower lycopene blood levels. One study suggests that higher lycopene blood levels are associated with a lower risk of developing cataracts. Your email address will not be published. Scientists  have found that patients with prostate cancer were found to have low levels of lycopene and high levels of oxidation of serum lipids and proteins. enable_page_level_ads: true Clinical trials utilizing lycopene in prostate cancer patients with various different clinical presentations (e.g., early stage, prostate-specific antigen (PSA) relapse, advanced disease) have yielded inconsistent results. Kopec R, Schwartz SJ, Hadley C: Lycopene. Some early research shows that a diet high in lycopene, primarily from tomatoes, seems to lower the risk of developing pancreatic cancer. Lycopene is likely safe when taken by mouth in appropriate amounts. Gingivitis. Research about how lycopene affects the risk of cervical cancer is inconsistent. Enlarged prostate (benign prostatic hypertrophy). : Encyclopedia of Dietary Supplements. It is found in intensive concentrations in the testes and seminal plasma and decreased levels have been demonstrated in men suffering from infertility. Lycopene antioxidant effect is twice as high as that of beta carotene and ten times higher than that of alpha tocopherol. Lycopene health benefits include treating neurological disorder, preventing stroke, supporting immune system, preventing macular degeneration, alleviating osteoporosis, fighting diabetes, treating prostate cancer, controlling cholesterol level, treating infertility, and promoting hair growth. The appropriate dose of lycopene depends on several factors such as the user’s age, health, and several other conditions. Evidence is strongest for lycopene protective effect against cancer of the lung, prostate, and stomach. FDA concluded that there was very limited credible evidence for qualified health claims for tomatoes and/or tomato sauce and a reduced risk for prostate, gastric, ovarian, and pancreatic cancers provided that the qualified health claims were appropriately worded so as to not mislead consumers” 29). Early research shows that taking lycopene by mouth for 3 months does not improve the response to radiotherapy and chemotherapy in people with brain tumors. Eating healthy foods has an undeniable positive effect on the body. Lycopene inhibits androgen receptor expression in prostate cancer cells in vitro and along with some of its metabolites, reduces prostate cancer cell proliferation and may modulate cell-cycle progression 23). Based on the above, FDA concludes that there is no credible evidence supporting a relationship between tomato or tomato-based food consumption and breast cancer. Research on the effect of lycopene in age-related eye disease is inconsistent. Its name is derived from the tomato’s species classification, “Solanum lycopersicum“. These foods deliver all the lycopene befits that exist. One petitioner also requested that FDA review the relationship between tomato and/or lycopene consumption and the risks of other forms of cancer, including lung, colorectal, gastric, breast, cervical, ovarian, endometrial, and pancreatic cancers. For cancers, as pointed by the FDA (see below), “there was no credible evidence to support qualified health claims for tomatoes or tomato-based foods and a reduced risk for lung, colorectal, breast, cervical, or endometrial cancer. When adverse effects occurred, they tended to present as gastrointestinal symptoms and, in one study, the symptoms resolved when lycopene was taken with meals. The antioxidant lycopene may exert useful effects on human sperm as well as eggs, according to preliminary research. The FDA found very limited evidence to support an association between tomato consumption and reduced risks of prostate, ovarian, gastric, and pancreatic cancers 32). Lycopene. Were given 2000 micrograms of lycopene, twice a day for 3 months. Heart disease. Lycopene reduces the risk of skin redness by half. Lycopene-rich tomatoes linked to lower stroke risk. However, the 11 conjugated and two non-conjugated double bonds in lycopene make it highly reactive towards oxygen and free radicals, and this anti-oxidant activity probably contributes to its efficacy as a chemoprevention agent 22). Cataracts. Free radicals are molecules that have at least one unpaired electron. LycoRed® softules, providing a total daily dose of 10 milligrams of lycopene, have been taken daily for three months. What is Grapefruit Seed Extract Good For. High cholesterol. Your email address will not be published. Lycopene is a powerful phytonutrient, an antioxidant with the ability to neutralize free radicals in key parts of the body, which helps it prevent chronic inflammation and disease. However, other research shows that neither lycopene intake nor lycopene blood levels are linked to breast cancer risk. The man in the Harvard study with the greatest protection against cancer consumed at least 6.5 mg per day. The few human intervention trials have been small and generally focused on intermediate endpoints and not response of clinically evident disease or overall survival and thus have limited translation to practice 11), 12). Some research shows that taking a specific lycopene supplement twice daily starting between weeks 16 and 20 of pregnancy and continuing until delivery lowers blood pressure and reduces associated complications. Based on the scientific evidence, FDA concludes that there is no credible evidence to support a qualified health claim for tomato lycopene; tomatoes and tomato products, which contain lycopene; lycopene in tomatoes and tomato products; lycopene in fruits and vegetables, including tomatoes and tomato products, and lycopene as a food ingredient, a component of food, or as a dietary supplement and reduced risk of prostate cancer 30). Lycopene Supplements may give you a purified form of lycopene, but you’re not sure you’re getting what you get from food. Lycopene also protects your eyes from oxidative stress that causes common eye diseases, making it one of the stronger eye vitamins you can consume. It is accepted that lycopene can help reduce blood LDL cholesterol (the \"bad\" cholesterol). Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. 2. More evidence is needed to rate lycopene for these uses. To treat gum disease, LycoRed® (providing eight milligrams of lycopene) has been taken by mouth daily in divided doses for two weeks 44). Lycopene may also affect the insulin-like growth factor (IGF) intracellular pathway in prostate cancer cells. Kidney cancer (renal cell carcinoma). The evidence for a relationship between tomato or tomato-based foods intake and a reduced risk of lung cancer is from one cohort study, one sub-cohort study and one nested case-control study. 25 September 2012 By superfoods Leave a Comment. Research suggests that increased lycopene consumption in the diet does not decrease the risk of developing diabetes. Two capsules of LycoRed® (each containing 15 milligrams of lycopene) have been taken by mouth once daily for 21 days 38). Evidence strongly suggests lycopene is protective against lung, stomach and prostate cancers. 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